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SENIOR SCIENTIST, RHEUMATOID ARTHRITIS-1353130206
The Immunology Therapeutic Area of Janssen Research & Development is committed to delivering transformational solutions for patients with autoimmune and inflammatory diseases. The goal of the newly-formed Disease Integrative Biology group, within the Immunology Therapeutic Area (TA), is to create a critical platform for deep biological disease understanding that will allow the Immunology TA, through enabling its R&D pipeline, to maintain its leadership position in providing treatments for autoimmune and inflammatory diseases. The Disease Integrative Biology group is seeking a highly motivated Senior Scientist to be an active member of a team focused upon creating the platform for biological disease understanding of Rheumatoid Arthritis (RA) and, utilizing these platforms to impact the R&D efforts focused on the RA near- and long-term portfolio.
Janssen Research & Development is recruiting for a Senior Scientist, Rheumatoid Arthritis (RA) in Spring House, PA.
The primary responsibility for this role is to support the development of the disease platform by developing and utilizing in vitro multi-cellular and organotypic models that reflect pathways associated with RA. He/she c will be expected to have a good understanding of the needs of the platform for the biological disease understanding of RA and, independently identify and execute on establishing appropriate in vitro model systems to generate data for the platform.The successful candidate should be able to integrate the in vitro techniques with novel technologies to discover new biology related to autoimmune diseases.In addition the candidate will be expected to independently generate hypothesis through utilization of the platform, validate hypotheses at the bench and, study the mechanism of action of exploratory drugs and drug targets. This position will require an interactive and pro-active scientist willing to work in a matrixed-team environment and will be expected to integrate into a multidisciplinary team effort consisting of internal and external scientists with expertise in immunology, cellular and molecular biology.
The Senior Scientist will be accountable for operational excellence, including transparency and rigor in data collection and interpretation to ensure high and consistent quality of documentation and presentation to Senior Management for decision making. This includes i) the provision of scientific expertise and education as necessary to key partner lines within the TA, ii) tracking of progress/impact of funded research, iii) regular updates of the research progress, iv) maintenance of written records of work in the form of notebooks, technical reports and protocols. He/she will be expected to pro-actively contribute in rendering the TA and Research Immunology the preferred partner of choice within Academia and represent Research Immunology to external partners and maintain a professional environment during the initial contact as well as continued discussions
This position requires a PhD with 3+ years of post-doctoral experience. The successful candidate must demonstrate a strong theoretical and technical grasp of immune-related molecular and cellular mechanisms and, expertise in immunological pathways related to RA. The successful candidate will have led the identification and introduction of novel technologies/approaches to solve complex biologic problems in RA.The He/she will be expected to critically appraise scientific literature in support of questions of importance for the Immunology TA's drug pipeline. He/she must be experienced in independently planning and executing experiments, developing reagents, methods and assays, recording and interpreting data, and, provide timely and rigorous data in oral and written form. The successful candidate will be expected to be actively engaged in bench-based, hands-on research and will be expected to provide direction, consulting, mentoring and training of Associate Scientists. The position is located in Spring House, PA.
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Primary Location:North America-United States-Pennsylvania-Spring House
Organization:Janssen Research & Development, LLC. (6084)
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